Blood Banking and Transfusion

Business outline

Kawasumi Laboratories, Inc., a predecessor company of SB-KAWASUMI, has been operating globally in the field of blood banking and transfusion including plastic blood containers ever since it commercialized the first Japanese disposable plastic blood collection/transfusion kit in 1954.

Demand for blood derivatives used in transfusion, which are essential for the medical treatment, is expected to grow along with the population increase and economic development in emerging countries as well as the increasing aging population in advanced countries. There is also an increasing need for safety of blood derivatives; e.g. prevention of side effects of blood transfusion.

From blood collection to blood transfusion

Plastic blood containers and apheresis kits are used to aseptically perform blood collection, blood derivatives formation, storage and blood transfusion in a fully-closed system. They are equipped with a filter to remove leucocytes, one of the causes for side effects of blood transfusion, which makes it possible to provide the healthcare industry with blood derivatives for transfusion with leucocytes removed.

SB-KAWASUMI is determined to keep supporting demand for safe bloods with its advanced technology and high quality established through the development and production of blood-related medical devices.


KARMI Blood Bag

~ Single and Multiple Blood Collection System

KARMI Blood Bag image


  • Ultra smooth siliconized needle minimizes patient's pain and discomfort during venipuncture
  • Inner surface of the bag is specially designed to minimize trauma to red cell and platelet cellular components
  • Rounded corners allow for smoother transfer of blood during the separation and transfusion processes, and results in a smaller volume of blood remaining in the bag
  • Anti-needle stick protector covers donor needle upon removal from the vein to prevent accidental needle stick injuries
  • Pre-attached vacuum tube holder facilitates secure blood sampling collection
  • Sampling pouch to collect the first portion of blood from donor and prevents contamination from indigenous bacterial on the skin

KARMI Blood Bag Detail

KARMI Blood Bag System

Top & Bottom System

The Top & Bottom blood bag system is available to assure the secure separation into each blood component.

~ In-Line Leukoreduction System

Significant effects of universal leukoreduction

  • Prevention of leukocyte alloantibody production  (NHFTR, PLT TR refractoriness)
  • Prevention of transfusion transmitted infections  (CMV, HTLV, Yersinia E, vCJD)
  • Reduction of transfusion associated immunological reactions  (PTP, TAGVHD)

For Whole Blood

Filtration time <30min. (RT filtration within 24 hours after blood collection)
Residual Leukocytes* <1×106 ⁄ unit
RBC Recovery >90%
Hemolysis* <0.8% (at the end of storage)
Leukoreduced RBC Hemoglobin >43g ⁄ unit
Residual blood in the filter <35mL

In-house evaluation,2014
*Complies with EU guidelines

For Red Cell

Filtration time <45min. (RT filtration within 24 hours after blood collection)
Residual Leukocytes* <1×106 ⁄ unit
Hemolysis* <0.8% (at the end of storage)
Leukoreduced RBC Hemoglobin* min.40g ⁄ unit
Residual blood in the filter <30mL

In-house evaluation,2016
*Complies with EU guidelines


~Platelet Storage Bag

KARMI PO Bag image


  • Made from Polyolefin to store platelets with high oxygen permeability
  • Collection, preservation, transportation and transfusion of platelets
  • Superior high oxygen permeability insures adequate oxygen for platelets
  • Safer due to no plasticizing and stabilizing agents
  • Superior in heat and cold resistance

Potassium Adsorption Filter

~Reducing Risk of Hyperkalemia and Making Safer Blood

Potassium Adsorption Filter image


  • Adsorption and removal of excessive potassium from packed red blood cells with SAG-M preservative solution (RBC-SAGM) that have been irradiated and/or stored for a long period of time
  • Intended patients: fetuses, premature infants, neonates, infants who are receiving exchange transfusions or extracorporeal circulation treatments or patients who urgently need rapid and massive blood transfusion to safe their life


  • Effects an exchange of excessive potassium ions (K+) with sodium ions (Na+) in RBC-SAGM
  • When dealing with human RBC-SAGM containing potassium concentration of 30 to 50mEq/L, at least 80% of the potassium is removed
    The small volume: flow rate of less than 30mL/min.
    The large volume: flow rate of less than 50mL/min.